Roger Smith Selected Research

Lung Injury

1/2022	Can nebulised HepArin Reduce morTality and time to Extubation in patients with COVID-19 Requiring invasive ventilation Meta-Trial (CHARTER-MT): Protocol and statistical analysis plan for an investigator-initiated international meta-trial of prospective randomised clinical studies.
1/2021	INHALEd nebulised unfractionated HEParin for the treatment of hospitalised patients with COVID-19 (INHALE-HEP): Protocol and statistical analysis plan for an investigator-initiated international metatrial of randomised studies.
3/2018	Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT.

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Roger Smith Research Topics

Disease

14	Neoplasms (Cancer) 02/2020 - 05/2002
12	Birth Weight (Birth Weights) 01/2021 - 04/2002
11	Premature Birth (Birth, Premature) 01/2023 - 01/2015
9	Asthma (Bronchial Asthma) 08/2010 - 04/2002
8	Inflammation (Inflammations) 08/2023 - 05/2008
8	Premature Obstetric Labor (Premature Labor) 08/2023 - 04/2004
7	Breast Neoplasms (Breast Cancer) 05/2008 - 05/2002
6	Infections 01/2022 - 09/2008
5	COVID-19 01/2022 - 01/2020
5	Pre-Eclampsia (Preeclampsia) 04/2018 - 04/2013
4	Pregnancy Complications 01/2022 - 11/2017
3	Chorioamnionitis 08/2023 - 01/2023
3	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2022 - 01/2015
3	Lung Injury 01/2022 - 03/2018
3	Thrombosis (Thrombus) 01/2022 - 01/2020
3	Tendon Injuries 03/2020 - 11/2015
3	Obesity 02/2020 - 01/2015
3	Thyroid Neoplasms (Thyroid Cancer) 11/2019 - 01/2017
3	Retinopathy of Prematurity (Retrolental Fibroplasia) 08/2018 - 01/2013
2	Sepsis (Septicemia) 03/2024 - 03/2013
2	Pain (Aches) 08/2023 - 06/2011
2	Chronic Disease (Chronic Diseases) 07/2023 - 02/2013
2	Mental Disorders (Mental Disorder) 01/2023 - 01/2017
2	Albuminuria 01/2023 - 04/2018
2	Pneumonia (Pneumonitis) 01/2022 - 01/2010
2	Osteoarthritis 03/2020 - 01/2017
2	Papillary Thyroid Cancer 01/2020 - 01/2016
2	Neoplasm Metastasis (Metastasis) 11/2019 - 11/2019
2	Compression Fractures (Compression Fracture) 11/2019 - 09/2014
2	Maternal Death 03/2019 - 11/2017
2	Hypertension (High Blood Pressure) 04/2018 - 12/2007
2	Proteinuria 04/2018 - 04/2013
2	Stillbirth 10/2017 - 01/2015
2	Hyperthyroidism 01/2017 - 01/2016
2	Postpartum Depression (Post-Natal Depression) 01/2017 - 01/2013
2	Choriocarcinoma 04/2013 - 08/2002
2	Vascular System Injuries 08/2010 - 10/2008
2	Colonic Neoplasms (Colon Cancer) 10/2009 - 09/2004
2	Adenocarcinoma 05/2008 - 05/2002
1	Parkinson Disease (Parkinson's Disease) 01/2023
1	Synucleinopathies 01/2023
1	Substance-Related Disorders (Drug Abuse) 01/2023
1	Rib Fractures (Rib Fracture) 01/2023
1	Respiratory Insufficiency (Respiratory Failure) 01/2022

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 01/2023 - 08/2002
11	Hormones (Hormone)IBA 12/2022 - 08/2002
7	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2022 - 07/2002
7	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2021 - 04/2002
6	Messenger RNA (mRNA)IBA 08/2023 - 04/2002
6	GlucocorticoidsIBA 08/2010 - 04/2002
5	Heparin (Liquaemin)FDA LinkGeneric 01/2022 - 01/2010
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2018 - 09/2004
4	Progesterone FDA LinkGeneric 08/2023 - 01/2010
4	RNA (Ribonucleic Acid)IBA 01/2023 - 08/2002
4	FibrinIBA 01/2022 - 01/2008
4	Estrogen Receptor alphaIBA 10/2017 - 03/2003
4	CytokinesIBA 01/2015 - 08/2008
4	Retinaldehyde (Retinal)IBA 06/2013 - 11/2011
4	PPAR gammaIBA 05/2008 - 03/2003
4	Cyclin D1IBA 05/2008 - 03/2003
3	Biomarkers (Surrogate Marker)IBA 11/2019 - 10/2008
3	CreatinineIBA 04/2018 - 12/2007
2	Tocolytic Agents (Tocolytics)IBA 01/2023 - 04/2004
2	Phosphotransferases (Kinase)IBA 01/2023 - 01/2010
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2020 - 08/2010
2	Aldehyde OxidaseIBA 02/2020 - 10/2017
2	Nerve Growth Factor (NGF)IBA 11/2019 - 11/2019
2	AngiotensinogenIBA 04/2018 - 04/2013
2	ElementsIBA 12/2017 - 06/2003
2	Oxytocin (Pitocin)FDA LinkGeneric 01/2017 - 01/2013
2	Thyrotropin Receptors (Thyrotropin Receptor)IBA 01/2017 - 01/2016
2	Estriol (Epiestriol)IBA 01/2017 - 04/2002
2	SCH 351591IBA 08/2010 - 10/2008
2	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 08/2010 - 10/2008
2	ChemokinesIBA 05/2010 - 08/2008
2	Interleukin-8 (Interleukin 8)IBA 05/2010 - 02/2009
2	NF-kappa B (NF-kB)IBA 01/2010 - 05/2009
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 10/2009 - 07/2008
2	SurvivinIBA 10/2009 - 07/2008
2	Peptides (Polypeptides)IBA 04/2009 - 07/2005
2	1,1- bis(3'- indolyl)- 1- (4- t- butylphenyl)methaneIBA 05/2008 - 09/2004
2	Retinoblastoma ProteinIBA 09/2004 - 05/2002
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2004 - 06/2003
1	Opioid Analgesics (Opioids)IBA 08/2023
1	MolybdenumIBA 07/2023
1	AntioxidantsIBA 07/2023
1	Oxidoreductases (Dehydrogenase)IBA 01/2023
1	Leucine (L-Leucine)FDA Link 01/2023
1	OctopamineIBA 01/2023
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2023
1	Peptide Hormones (Polypeptide Hormones)IBA 12/2022
1	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 01/2022
1	pro-corticotropin releasing hormoneIBA 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022

Therapy/Procedure

9	Therapeutics 03/2024 - 03/2013
2	Artificial Respiration (Mechanical Ventilation) 01/2021 - 01/2010
2	Anesthesia 01/2020 - 06/2011
2	Prenatal Care (Care, Prenatal) 01/2018 - 11/2017
2	Lasers (Laser) 01/2006 - 07/2005
1	Euthanasia (Mercy Killing) 01/2023